St. Louis, Missouri Gout Clinical Trials

Gout affects 3 to 5 million individuals in the United States and is increasing in incidence and prevalence. Gout is a serious health condition characterized by flares of acute arthritis, chronic gouty arthropathy, tophi and uric acid urolithiasis, and is associated with a broad range of comorbidities, including cardiovascular (CV) disease, chronic kidney disease, diabetes and obesity. Certain medications may contribute to increased uric acid in the blood such as the water pill and may be associated with gout. Gout is mainly seen in males, postmenopausal women, and people who drink alcohol and may run in families as well. The underlying cause of gout is elevated blood uric acid levels (hyperuricemia.) Hyperuricemia develops into gout when urate crystals are formed from supersaturated body fluids and are deposited in joints, tophi, and parenchymal organs thus causing acute inflammatory responses that can be very painful and long lasting.


Medications to treat gout work to lower uric acid levels in the blood and to alleviate pain associated with flare ups. Visit the studies page to view any current gout and uric acid studies you may be interested in or contact us with the patient contact form.